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Murders at Karlov Manor is the ninety-ninth Magic expansion. It is a backdrop set taking place on Ravnica and will be released on February 9th, 2024.

Murders at Karlov Manor is a top-down designed murder mystery set, featuring the tropes of the genre. Murders and mysteries are woven into the game itself. Play detective as you collect evidence, don disguises and identify suspects to decipher the deadly murder mystery at the heart of Ravnica.

Karlov Manor contains 286 regular cards (81 commons, 100 uncommons, 70 rares, 20 mythic rares, 15 basic lands), and includes randomly inserted traditional foil versions of all cards. The rare double cycle of surveil lands comes from a separate print sheet. The regular cards include 5 full-art "Impossible" basic lands (#271-276). These invoke mathematically-inspired visuals with irregular perspectives, each one a puzzle to ponder on its own. Alternate card frames have a different number than the original version. The Story Spotlight Showcase "Magnified" cards are #287-316. Utilizing the frame introduced for Ravnica with March of the Machine, the "Ravnica City" card treatment frames each card with Ravnica's signature city spires (#317-323). Double-rainbow foil serialized versions of the cards with the "Ravnica City" treatment, each with 250 English-only copies, can only be found in Collector Boosters (same number with an added z). Borderless cards - surveil lands, Kellan and Kaya - are #324-335. Cards with the Showcase "Dossier" treatment are #336-376. Select "Dossier" cards have "invisible" ink versions, adding surprise elements for players to uncover in their search (#377-388). These Showcase "Dossier Invisible Ink" cards are only available in Collector Boosters. Extended art cards and #389-422. The promos are #423-432.